Description
MOTS-c 40mg | Mitochondrial-Derived Research Peptide
IMPORTANT: RESEARCH USE ONLY
MOTS-c is supplied as a lyophilized peptide powder intended exclusively for scientific and laboratory research purposes (Research Use Only, RUO).
This material is not intended for human or veterinary use, human consumption, diagnostic procedures, or therapeutic applications.
Also Known As: MOTS-c, Mitochondrial Open Reading Frame of the 12S rRNA-c, Mitochondrial-Derived Peptide (MDP)
PRODUCT OVERVIEW
MOTS-c is a mitochondrial-derived peptide (MDP) consisting of 16 amino acids and encoded within the 12S rRNA region of mitochondrial DNA (mtDNA).
Mitochondrial-derived peptides have become an area of scientific interest due to their involvement in cellular signalling and the communication of metabolic information between mitochondria and other cellular systems.
MOTS-c has been investigated in research involving mitochondrial signalling, cellular metabolism, energy homeostasis, glucose metabolism, metabolic adaptation, and cellular responses to metabolic stress.
Experimental studies have also examined MOTS-c in connection with cellular energy-sensing pathways, including AMP-activated protein kinase (AMPK), as well as broader mechanisms involved in mitochondrial and metabolic regulation.
Each vial contains 40mg of MOTS-c in lyophilized form.
RESEARCH BACKGROUND
Mitochondria are widely recognised for their central role in cellular energy production, but research has increasingly demonstrated that mitochondria also participate in complex signalling processes.
MOTS-c belongs to a group of small peptides encoded by mitochondrial genetic material that are collectively referred to as mitochondrial-derived peptides.
Research into MOTS-c has focused on understanding how mitochondrial signalling may influence cellular responses to changes in energy availability, nutrient conditions, metabolic demand, and cellular stress.
These characteristics have made MOTS-c a compound of interest in experimental research involving mitochondrial biology, molecular signalling, cellular metabolism, and metabolic homeostasis.
MECHANISM OF RESEARCH INTEREST
Scientific research has investigated MOTS-c in relation to AMP-activated protein kinase (AMPK), an important cellular energy-sensing pathway.
AMPK is involved in coordinating cellular responses to changes in energy availability and participates in the regulation of processes associated with glucose metabolism, lipid metabolism, cellular energy utilisation, and mitochondrial activity.
MOTS-c has also been studied in the wider context of mitochondrial-to-nuclear communication and cellular adaptation to metabolic stress.
The biological mechanisms associated with MOTS-c remain an active area of scientific investigation, and experimental findings may vary depending on the research model and conditions used.
RESEARCH APPLICATIONS
- Mitochondrial-derived peptide research
- Mitochondrial signalling studies
- Cellular energy metabolism research
- AMPK pathway investigations
- Metabolic regulation and energy homeostasis research
- Glucose metabolism studies
- Cellular stress-response research
- Mitochondrial-to-nuclear signalling studies
- Energy-sensing pathway research
- Metabolic adaptation investigations
- Mitochondrial biology research
- Cellular ageing and metabolic pathway research
- Peptide signalling studies
PRODUCT SPECIFICATIONS
Product Name: MOTS-c
Full Name: Mitochondrial Open Reading Frame of the 12S rRNA-c
Active Ingredient: MOTS-c
CAS Number: 1627580-64-6
PubChem CID: 155885767
Peptide Sequence: MRWQEMGYIFYPRKLR
Peptide Length: 16 amino acids
Molecular Weight: Approximately 2174.6 g/mol
Appearance: White to off-white lyophilized powder
Physical Form: Lyophilized Powder
Quantity: 40mg per vial
Product Classification: Research Use Only (RUO)
Packaging: Sealed research vial
STORAGE & HANDLING
Long-Term Storage: Store at -20°C in the original sealed container for optimal long-term storage.
Short-Term Storage: Store refrigerated at 2 to -8°C where appropriate for the individual product batch.
Protect from direct light, excessive heat, and moisture.
Keep the vial tightly sealed during storage.
Minimize unnecessary temperature fluctuations.
Avoid repeated freeze-thaw cycles.
After Reconstitution: Store refrigerated at 2 to -8°C, protect from light, and avoid repeated temperature cycling.
Recommended Research Use Period After Reconstitution: Where supported by the product’s batch-specific stability documentation, use the prepared research solution within 28 days when stored under the specified refrigerated conditions.
Batch-specific storage and stability information provided with the product or Certificate of Analysis should take precedence.
RESEARCH SAFETY INFORMATION
MOTS-c is an experimental research peptide intended for controlled scientific and laboratory investigation.
The material should be handled by appropriately trained personnel using suitable laboratory procedures and personal protective equipment.
Information regarding MOTS-c is provided as a summary of areas investigated within scientific research. Research into mitochondrial-derived peptides and their biological mechanisms remains ongoing.
Scientific Information Notice: The information provided above is for research reference only. It does not constitute medical advice, dosing guidance, treatment recommendations, or instructions for human use.
REGULATORY & RESEARCH USE NOTICE
FOR RESEARCH USE ONLY. NOT FOR HUMAN OR VETERINARY USE.
This product is intended solely for scientific and laboratory research.
MOTS-c is not supplied as an approved medicinal product. It is not intended for human consumption, diagnosis, treatment, prevention of disease, or any clinical or therapeutic application.
Purchasers are responsible for ensuring that the purchase, possession, storage, handling, and use of this material comply with all applicable laws, regulations, institutional requirements, and laboratory safety procedures.
Product-specific information, including batch testing and purity where applicable, should be referenced against the relevant Certificate of Analysis (COA).
Images for illustration purposes only.
